HomeWhat's NewVideosArticlesDownloadsCalendarWeb LinksSite MapO.R. Schedule
USC - University of Southern California Cardiothoracic Surgery at University of Southern California Keck School of Medicine
Department InformationPatient's GuideFaculty & StaffAreas of ExpertiseDiseases & TreatmentsContact Us

Clinical Trials

Safety and Efficacy Study of the Medtronic CoreValve® System in the Treatment of Symptomatic Severe Aortic Stenosis in High Risk and Very High Risk Subjects Who Need Aortic Valve Replacement

ClinicalTrials.gov link:
http://clinicaltrials.gov/ct2/show/NCT01240902?term=corevalve&rank=4

The purpose of the study is to evaluate the safety and efficacy of the Medtronic CoreValve® System in the treatment of symptomatic severe aortic stenosis in subjects who have a predicted high risk for aortic valve surgery and/or very high risk for aortic valve surgery.

Medtronic CoreValve System
Medtronic CoreValve® System

 

Condition:
Severe Aortic Stenosis - a heart valve disorder that narrows or obstructs the aortic valve opening. This prevents the aortic valve from opening properly, resulting in increased pressure inside the left ventricle and obstructing blood flow from the left ventricle to the aorta.

Aortic Valve, Aorta and Left Ventricle

Intervention:
Device: Medtronic CoreValve® System Transcatheter Aortic Valve Implantation (TAVI)
Device: Surgical Aortic Valve Replacement (SAVR)

Eligibility for enrollment:

  • Advanced age (usually > 75 years, but not exclusively)
  • Symptomatic severe aortic stenosis (NYHA Class II or greater)
  • High risk for surgical aortic valve replacement
  • Left ventricular ejection fraction > 20% by resting echocardiogram

Primary Investigators:

Co-Investigators:

 

 

> Return to Clinical Trials

 

Share this page: 

 

Find us on Facebook
In This Section

Faculty and Staff | Patient's Guide | Areas of Expertise | Diseases & Treatments | Contact Us
Home | What's New | Videos | Articles | Downloads | Calendar | Web Links | Site Map

University of Southern California, 1520 San Pablo Street, HCC2 Suite 4300, Los Angeles, CA 90033
Phone: 323.442.5849     Fax: 323.442.5956     E-mail: ctinfo@surgery.usc.edu
Copyright © USC Cardiothoracic Surgery